Methadone hydrochloride tablets are an opioid agonist shown for the management of moderate to extreme pain when a persistent, around-the-clock opioid pain relieving is required for an extended period of time.detoxification treatment of opioid addiction (heroin or other morphine-like drugs).maintenance treatment of opioid compulsion (heroin or other morphine-like drugs), in conjunction with fitting social and therapeutic administrations.
IMPORTANT RISK INFORMATION
MANHANDLE POTENTIAL, LIFE-THREATENING RESPIRATORY DEPRESSION, LIFE-THREATENING QT PROLONGATION, INADVERTENT INTRODUCTION, AND TREATMENT FOR OPIOID ADDICTION.
- Methadone is contraindicated in patients with:
- Significant respiratory depression.
- Acute or severe bronchial asthma.
- Known or suspected paralytic ileus.
- Hypersensitivity to methadone.
NOTICES AND PRECAUTIONS
Monitor patients with significant chronic obstructive pulmonary disease or cor pulmonale, and patients having a substantially diminished respiratory save, hypoxia, hypercapnia, or pre-existing respiratory misery for respiratory sadness, especially when starting treatment and titrating with methadone hydrochloride tablets, as in these patients, indeed regular helpful dosages of methadone hydrochloride tablets may diminish respiratory drive to the point of apnea.
Hypotension, significant sedation, coma, or respiratory sadness may result in the event that methadone hydrochloride tablets are utilized concomitantly with other CNS depressants (e.g., narcotics, anxiolytics, hypnotics, neuroleptics, other opioids).
Opioids may too darken the clinical course in a understanding with a head injury.Methadone hydrochloride tablets may cause fit of the sphincter of Oddi.
Shipping & Storage
LIGHT SENSITIVE, AIR SENSITIVE: Keep tightly closed in light-resistant containers.
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